Staff & Leadership

David Dowdy, MD, PhD

David Dowdy, MD, PhD - Photo

Biography

Associate Professor
Department of Epidemiology, Bloomberg School of Public Health
The Johns Hopkins University

Research interests

HIV/TB coinfection, diagnostic epidemiology, mathematical modeling, economic evaluation 

Methods of expertise

I am an infectious disease epidemiologist and practicing general internist with cross-cutting expertise in diagnostic epidemiology, implementation science, mathematical/mechanistic modeling, and economic evaluation/cost-effectiveness analysis. My area of greatest content expertise is the epidemiology of tuberculosis (TB), including TB diagnosis/case-finding and the interplay between TB and HIV coinfection. I am also interested in the mechanistic modeling of HIV transmission in the United States, and I work closely with other members of the CFAR on agent-based and compartmental models of domestic HIV transmission. I work in diverse field sites including South Africa, Uganda, Malawi, Zambia, Pakistan, and Vietnam. I also have a defined interest in training and mentorship, specifically of junior investigators interested in transdisciplinary research that spans epidemiology, quantitative modeling methods, economic evaluation, and clinical research.

Services available to CFAR investigators

Cost-effectiveness analysis, mathematical modeling, diagnostic evaluation, quantitative implementation studies, study design, expertise in transmission dynamics and HIV/TB coinfection

Sample projects

  1. The Impact of Pre-Exposure Prophylaxis Among Men Who Have Sex With Men: A Modeling Study

    Our team has developed, in collaboration with the CDC and Baltimore City Health Department, an agent-based simulation of HIV transmission and impact of prevention activities among MSM.
     
  2. Active TB Case-Finding in Rural South Africa

    We are conducting an R01-funded cluster-randomized trial of active case-finding approaches in a rural area of South Africa with high rates of HIV coinfection. We are comparing facility-based screening, household contact investigation, and incentive-based contact tracing.
     
  3. The Epidemiologic and Economic Impact of Improving HIV Testing, Linkage, and Retention in Care in the United States

    In collaboration with a team led by Dr. Maunank Shah, I have helped to develop a deterministic policy model of HIV prevention in the U.S. Results of this model have been published in Clinical Infectious Diseases and Lancet HIV.
     
  4. Cost-Effectiveness of Preventive Therapy for TB Among HIV-Positive Adults in Brazil

    I have worked with the TB/HIV in Rio (THRio) team in Rio de Janeiro, Brazil, to study the cost-effectiveness and population-level impact of TB preventive therapy among people living with HIV in that setting.
     
  5. Screening for Tuberculosis Among Adults Newly Diagnosed with HIV in Sub-Saharan Africa

    I work as part of a team led by Dr. Richard Chaisson to study the effectiveness (mortality reduction) and cost-effectiveness of screening for TB among adults newly diagnosed with HIV in rural Malawi.